Sarcopenia

Where the papers sit

13 papers from the last 6 months study sarcopenia directly · updated from PubMed 10 Oct 2026

• Sarcopenia in Aging and Cancer

  Exercise, electroacupuncture and online multicomponent programs are being tested to improve strength, function and nutrition-related traits in older adults. In cancer, low muscle mass and myosteatosis repeatedly mark treatment toxicity and worse survival, including with enzalutamide, in advanced disease and renal cell carcinoma with venous tumor thrombus. Population data add links with glycaemic control, blood pressure and lifestyle behaviours. The field is moving toward combining sarcopenia screening with supportive care and cancer-risk stratification, although intervention evidence remains narrower than prognostic evidence.

  6 papers · 46.2%

• Muscle Assessment and Prognosis

  Muscle mass, handgrip strength, performance and digital gait measures are being developed as complementary markers of sarcopenia and prognosis. Machine-learning indices and appendicular skeletal muscle mass are linked to survival or nonrelapse mortality in DLBCL and ALS, while sarcopenia contributes to SIRS risk after PCNL. Mechanistic work connects the phenotype to the brain-muscle axis through BDNF and to cGAS-STING signaling and mitochondrial homeostasis, with Jintiange reported to improve age-related disease. The direction is toward multimodal risk prediction, but thresholds and clinical utility remain unsettled.

  5 papers · 38.5%

• Nutritional Phenotypes of Sarcopenia

  Malnutrition, low muscle mass and excess adiposity are being treated as overlapping nutritional phenotypes rather than isolated conditions. In haemodialysis populations, their prevalence and overlap are assessed using SARC-F and BMI-based models. Sarcopenic obesity is also linked to urinary incontinence in older women, extending concern beyond muscle function. The main need is better clinical identification of these overlapping syndromes and their consequences.

  2 papers · 15.4%