Mortality
Mortality refers to the occurrence of death in a defined population or clinical cohort over a specified period.
Mortality refers to the occurrence of death in a defined population or clinical cohort over a specified period. In medicine and epidemiology, it is a core clinical metric used to quantify fatal outcomes, compare disease burden, evaluate treatment effectiveness, and inform risk stratification. Mortality may be reported as all-cause mortality or cause-specific mortality, and it is frequently analyzed alongside morbidity, survival, disease progression, and prognosis to characterize clinical outcomes across patient groups.
In biomedical research, mortality is often modeled using statistical approaches such as the Cox proportional hazards model, hazard ratio estimation, odds ratio analysis, and propensity score matching, with performance or prediction studies frequently reporting sensitivity, specificity, area under the curve, confidence interval, and P-value. Mortality is especially important in high-risk conditions such as infection, stroke, inflammation-related critical illness, and chronic cardiometabolic disease, where it serves as a key endpoint for evaluating clinical severity and the effectiveness of interventions or prognostic tools.
Where the papers sit
15 papers from the last 6 months study mortality directly · updated from PubMed 3 Nov 2026
Study type 0 clinical trials · 9 observational · 3 human data · 3 unclassified
Themes one subject · 1 new direction
Those 15 are all about one subject.
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Clinical Mortality Risk Assessment
Mortality risk assessment links patient characteristics, disease burden and care setting to survival and major adverse outcomes. Recurring applications include cancer, sepsis, diabetes, cardiovascular disease, liver disease and critical illness. AI and machine-learning models, wearable mobility measures and routine clinical markers such as alkaline phosphatase support individualized prognostic stratification. The evidence remains focused on prediction and validation rather than a single intervention or shared biological mechanism.
AI-based mortality prediction is evaluated as a population-level clinical intervention rather than merely as a prognostic endpoint
The Korean intensive-care study of an AI-based mortality-prediction strategy treated mortality prediction not simply as a risk estimate or model-performance target, but as an intervention whose implementation could alter lifetime costs and quality-adjusted survival. It found that activating the strategy at ICU admission was cost-effective, with an incremental cost-effectiveness ratio below the stated societal willingness-to-pay threshold. This makes mortality prediction itself a subject of health-economic adoption decisions, extending its role beyond the prognostic and outcome-measurement uses represented by the other papers 42612087Aug.
Papers
The 15 papers from the last 6 months that study mortality directly, newest first, by theme and by study type. Study types come from PubMed publication types and MeSH headings.
By theme
Clinical Mortality Risk Assessment (15)
- Association between the site of emergency care and patient-centered outcomes in patients with cancer: rationale and design of the French COVER cohort. European journal of emergency medicine : official journal of the European Society for Emergency Medicine · 12 Oct 2026 PMID 42861454
- Mild alkaline phosphatase elevation associates with increased mortality and major adverse liver outcomes in MASLD. Hepatology communications · 16 Sept 2026 PMID 42748409
- Wearable-derived postdischarge mobility as a digital biomarker for 90-day readmission and mortality in metastatic cancer. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 11 Sept 2026 PMID 42726154
- Machine Learning Model for Predicting Risk Factor Analysis and a Mortality Prediction Model of Acute Cholangitis Complicated with Sepsis. Journal of visualized experiments : JoVE · 9 Sept 2026 PMID 42714037
- Value of AI in Critical Care Using Real-World Evidence on Intensive Care Unit Mortality Prediction: Cost-Utility Analysis. Journal of medical Internet research · 18 Aug 2026 PMID 42612087
- AI for Prognosis Among People Living With HIV: Protocol for a Systematic Review and Meta-Analysis. JMIR research protocols · 18 Aug 2026 PMID 42612074
- Cardiac outcomes following SARS-CoV-2 infection versus BNT162b2 vaccination in adolescents and young adults: a cohort study of 4 million individuals. Vaccine · 17 Aug 2026 PMID 42607625
- Country-specific burden of type 2 diabetes mellitus in the Caribbean, 1990-2023: Insights from the global burden of disease study. Diabetes research and clinical practice · 14 Aug 2026 PMID 42600892
- Association of GLP-1 Receptor Agonist Use With Cardiovascular Outcomes and Mortality in Japanese Patients With Type 2 Diabetes: A Real-World Claims Database Study. Diabetes, obesity & metabolism · 12 Aug 2026 PMID 42581431
- The phoenix sepsis score for high mortality risk identification and prognostic predict in pediatric liver transplant recipients. European journal of pediatrics · 3 Aug 2026 PMID 42547621
- Diabetic Foot Ulcers Are Clinical Marker of Disease Burden in People With Diabetes and Heart Failure. Diabetes, obesity & metabolism · 21 Jul 2026 PMID 42482123
- Predicting severe toxicities and mortality in older patients with colorectal cancer: An analysis of 3 clinical trials and 3 prospective cohorts. European journal of cancer (Oxford, England : 1990) · 15 Jul 2026 PMID 42456539
- Clinical outcomes of conservative, endovascular and microsurgical management of unruptured giant intracranial aneurysms: 3-year follow-up of the prospective, multinational Giant Intracranial Aneurysm Registry. Journal of neurology, neurosurgery, and psychiatry · 7 Jul 2026 PMID 42414088
- Development and Validation of an XGBoost-SHAP Model for Predicting Adverse Outcomes in Elderly Cardiovascular Patients With Polypharmacy: A Retrospective Cohort Study. Pharmacology research & perspectives · 1 Jul 2026 PMID 42384558
- The Role of Epicardial and Visceral Fat in Severe Respiratory Infections: Associations With Adverse Outcomes. Clinical obesity · 10 Jun 2026 PMID 42267655
By study type
Observational studies and case reports (9)
- Association between the site of emergency care and patient-centered outcomes in patients with cancer: rationale and design of the French COVER cohort. European journal of emergency medicine : official journal of the European Society for Emergency Medicine · 12 Oct 2026 PMID 42861454
- Mild alkaline phosphatase elevation associates with increased mortality and major adverse liver outcomes in MASLD. Hepatology communications · 16 Sept 2026 PMID 42748409
- Wearable-derived postdischarge mobility as a digital biomarker for 90-day readmission and mortality in metastatic cancer. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 11 Sept 2026 PMID 42726154
- Machine Learning Model for Predicting Risk Factor Analysis and a Mortality Prediction Model of Acute Cholangitis Complicated with Sepsis. Journal of visualized experiments : JoVE · 9 Sept 2026 PMID 42714037
- The phoenix sepsis score for high mortality risk identification and prognostic predict in pediatric liver transplant recipients. European journal of pediatrics · 3 Aug 2026 PMID 42547621
- Predicting severe toxicities and mortality in older patients with colorectal cancer: An analysis of 3 clinical trials and 3 prospective cohorts. European journal of cancer (Oxford, England : 1990) · 15 Jul 2026 PMID 42456539
- Clinical outcomes of conservative, endovascular and microsurgical management of unruptured giant intracranial aneurysms: 3-year follow-up of the prospective, multinational Giant Intracranial Aneurysm Registry. Journal of neurology, neurosurgery, and psychiatry · 7 Jul 2026 PMID 42414088
- Development and Validation of an XGBoost-SHAP Model for Predicting Adverse Outcomes in Elderly Cardiovascular Patients With Polypharmacy: A Retrospective Cohort Study. Pharmacology research & perspectives · 1 Jul 2026 PMID 42384558
- The Role of Epicardial and Visceral Fat in Severe Respiratory Infections: Associations With Adverse Outcomes. Clinical obesity · 10 Jun 2026 PMID 42267655
Human data, design not indexed (3)
- Value of AI in Critical Care Using Real-World Evidence on Intensive Care Unit Mortality Prediction: Cost-Utility Analysis. Journal of medical Internet research · 18 Aug 2026 PMID 42612087
- AI for Prognosis Among People Living With HIV: Protocol for a Systematic Review and Meta-Analysis. JMIR research protocols · 18 Aug 2026 PMID 42612074
- Country-specific burden of type 2 diabetes mellitus in the Caribbean, 1990-2023: Insights from the global burden of disease study. Diabetes research and clinical practice · 14 Aug 2026 PMID 42600892
Unclassified: not yet indexed with MeSH (3)
- Cardiac outcomes following SARS-CoV-2 infection versus BNT162b2 vaccination in adolescents and young adults: a cohort study of 4 million individuals. Vaccine · 17 Aug 2026 PMID 42607625
- Association of GLP-1 Receptor Agonist Use With Cardiovascular Outcomes and Mortality in Japanese Patients With Type 2 Diabetes: A Real-World Claims Database Study. Diabetes, obesity & metabolism · 12 Aug 2026 PMID 42581431
- Diabetic Foot Ulcers Are Clinical Marker of Disease Burden in People With Diabetes and Heart Failure. Diabetes, obesity & metabolism · 21 Jul 2026 PMID 42482123
Written from 15 PubMed abstracts, each one listed by PMID above. Published: 2026-08-19. Last written: 2026-09-18 by GPT. Drafted by language models from published abstracts; not medical advice.