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Heart failure

Heart failure is a clinical syndrome in which the heart is unable to pump blood sufficiently to meet the body’s metabolic demands, or can do so only at the cost of elevated filling pressures.

Where the papers sit

10 papers from the last 6 months study heart failure directly · updated from PubMed 10 Oct 2026

Study type 0 clinical trials · 6 observational · 3 human data · 1 unclassified

Themes 3 themes

  • Heart Failure Epidemiology and Biomarkers

    Heart failure work is defining population burden and associated clinical risks in routine care. Type 2 diabetes marks higher hospitalization risk and substantial healthcare utilization, while prevalence remains important in high-cardiovascular-risk patients. Iron deficiency is being characterized in primary care, and trimethyllysine is being explored as a biomarker. The shared direction is better risk stratification and comorbidity recognition, not a demonstrated therapeutic shift.

    4 papers · 40%

  • Cardiovascular Outcomes and Care

    Cardiovascular outcomes are being studied through improved event ascertainment, social context, risk linkage, and home-based care. Electronic medical record retrieval and large language models target more reliable identification of cardiovascular events. Other work connects neighborhood mortgage bias or atrial fibrillation with stroke and major adverse cardiovascular events, while telemonitoring examines home nursing implementation. The common direction is broader, more context-aware cardiovascular surveillance and care delivery.

    4 papers · 40%

  • Others — MPO Inhibition and Airway Microbiomes

    Molecular drug development and airway ecology occupy separate lines here. Mitiperstat work centers on population pharmacokinetics of myeloperoxidase inhibition, whereas respiratory microbiome work follows dysbiosis, mucociliary clearance, bronchiectasis, and infection. No shared clinical endpoint or mechanism links the two. The cluster therefore does not support a single direction.

    2 papers · 20%

Papers

The 10 papers from the last 6 months that study heart failure directly, newest first, by theme and by study type. Study types come from PubMed publication types and MeSH headings.

By theme

Heart Failure Epidemiology and Biomarkers (4)
  1. Prevalence and evolution of heart failure in patients with type 2 diabetes mellitus at high cardiovascular risk (HF-LANDMARK study). Journal of diabetes and its complications · 31 Aug 2026 PMID 42673923
  2. Iron deficiency in primary care patients with heart failure: a cross-sectional study of the heart failure in Southern Sweden (HISS) cohort. BMC cardiovascular disorders · 3 Jul 2026 PMID 42399800
  3. Heart failure hospitalization in patients with and without type 2 diabetes: A population-based retrospective cohort study. PloS one · 2 Jul 2026 PMID 42391246
  4. Trimethyllysine as a potential biomarker for heart failure. Clinica chimica acta; international journal of clinical chemistry · 22 Apr 2026 PMID 42019745
Cardiovascular Outcomes and Care (4)
  1. Neighborhood Contemporary Redlining and Racial Mortgage Lending Bias and Cardiovascular Outcomes in Women With Breast Cancer. Journal of the American Heart Association · 9 Sept 2026 PMID 42714450
  2. Diagnostic accuracy of electronic medical record retrieval methods and a large language model for identifying cardiovascular events: a multisite retrospective validation study in a medical system in the United States. BMJ open · 13 Aug 2026 PMID 42595369
  3. Implementation of a Multidevice Telemonitoring Program for Home-Based Nursing Care in Quebec: Qualitative Report. JMIR medical informatics · 16 Jun 2026 PMID 42302234
  4. Age-Dependent Association between Heart Failure and Stroke Risk in Atrial Fibrillation: A Nationwide Cohort Study. Journal of the American Heart Association · 6 May 2026 PMID 42089202
Others — MPO Inhibition and Airway Microbiomes (2)
  1. The respiratory microbiome: dynamics from health to disease. FEMS microbiology ecology · 22 Jun 2026 PMID 42329775
  2. Population Pharmacokinetics of the Novel Myeloperoxidase Inhibitor Mitiperstat. Pharmacology research & perspectives · 8 May 2026 PMID 42101107

By study type

Observational studies and case reports (6)
  1. Prevalence and evolution of heart failure in patients with type 2 diabetes mellitus at high cardiovascular risk (HF-LANDMARK study). Journal of diabetes and its complications · 31 Aug 2026 PMID 42673923
  2. Diagnostic accuracy of electronic medical record retrieval methods and a large language model for identifying cardiovascular events: a multisite retrospective validation study in a medical system in the United States. BMJ open · 13 Aug 2026 PMID 42595369
  3. Iron deficiency in primary care patients with heart failure: a cross-sectional study of the heart failure in Southern Sweden (HISS) cohort. BMC cardiovascular disorders · 3 Jul 2026 PMID 42399800
  4. Heart failure hospitalization in patients with and without type 2 diabetes: A population-based retrospective cohort study. PloS one · 2 Jul 2026 PMID 42391246
  5. Age-Dependent Association between Heart Failure and Stroke Risk in Atrial Fibrillation: A Nationwide Cohort Study. Journal of the American Heart Association · 6 May 2026 PMID 42089202
  6. Trimethyllysine as a potential biomarker for heart failure. Clinica chimica acta; international journal of clinical chemistry · 22 Apr 2026 PMID 42019745
Human data, design not indexed (3)
  1. Neighborhood Contemporary Redlining and Racial Mortgage Lending Bias and Cardiovascular Outcomes in Women With Breast Cancer. Journal of the American Heart Association · 9 Sept 2026 PMID 42714450
  2. Implementation of a Multidevice Telemonitoring Program for Home-Based Nursing Care in Quebec: Qualitative Report. JMIR medical informatics · 16 Jun 2026 PMID 42302234
  3. Population Pharmacokinetics of the Novel Myeloperoxidase Inhibitor Mitiperstat. Pharmacology research & perspectives · 8 May 2026 PMID 42101107
Unclassified: not yet indexed with MeSH (1)
  1. The respiratory microbiome: dynamics from health to disease. FEMS microbiology ecology · 22 Jun 2026 PMID 42329775