Hypertension
Hypertension is a chronic disease characterized by persistently elevated blood pressure and is a major vascular risk factor associated with cardiovascular disease, stroke, heart failure, and chronic kidney disease.
Hypertension is a chronic disease characterized by persistently elevated blood pressure and is a major vascular risk factor associated with cardiovascular disease, stroke, heart failure, and chronic kidney disease. Its clinical importance reflects its relationship with multiple organ systems: hypertension is studied alongside diabetes, obesity, dyslipidemia, smoking, renal function, proteinuria, and other determinants of cardiovascular and cardio-renal risk.
Management commonly involves blood-pressure monitoring, lifestyle measures, and antihypertensive medication. Some patients remain above treatment targets despite therapy; the EnligHTN study specifically examined catheter-based renal denervation in patients with resistant hypertension who were taking multiple antihypertensive drugs, representing a population with more difficult-to-control hypertension. Current research also evaluates hypertension through care cascades, treatment patterns, population disparities, genetic risk, and its relationships with heart failure, type 2 diabetes, brain white-matter microstructure, and mortality.
Where the papers sit
17 papers from the last 6 months study hypertension directly · updated from PubMed 1 Nov 2026
Study type 1 clinical trial · 13 observational · 1 human data · 2 unclassified
Themes one subject · 1 new direction
Those 17 are all about one subject.
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Hypertension Epidemiology and Care
Population studies are refining hypertension risk assessment through visceral adiposity, metabolic profiles, social factors and machine learning. Rural and national cohorts repeatedly show gaps in diagnosis, treatment and control, including among people with HIV and harder-to-control disease. Secondary endocrine hypertension and antihypertensive medication patterns broaden the clinical focus beyond routine essential hypertension. The work is moving toward earlier detection and more tailored follow-up, but largely observational evidence does not establish a single best intervention.
Hypertension is an effect modifier of the relationship between insulin resistance and cancer mortality
The metabolic score for insulin resistance and cancer mortality cohort study examined METS-IR and cancer-specific death, with hypertension functioning not simply as a cardiovascular risk factor, outcome, or treatment target but as a modifier of the METS-IR–mortality association. Higher METS-IR was associated with cancer mortality, and the strength of this association differed according to hypertension status. This reframes hypertension as a condition that changes the prognostic meaning of another metabolic exposure in relation to cancer death, rather than only as an endpoint or predictor in its own right 42175442May.
Papers
The 17 papers from the last 6 months that study hypertension directly, newest first, by theme and by study type. Study types come from PubMed publication types and MeSH headings.
By theme
Hypertension Epidemiology and Care (17)
- Association between Chinese visceral adiposity index and prevalent hypertension among older adults in rural China: A cross-sectional study. Clinical and experimental hypertension (New York, N.Y. : 1993) · 9 Oct 2026 PMID 42853626
- Facial nerve palsy and hypertension; unusual presentation of apparent mineralocorticoid excess (AME) syndrome in a paediatric patient. BMJ case reports · 7 Oct 2026 PMID 42843912
- Hypertension epidemiology and primary care indicators in Portugal: a contemporary nationwide analysis. Blood pressure · 1 Oct 2026 PMID 42822005
- Clinical course and management of adrenal endocrine hypertension: A single-center experience. Endocrine regulations · 19 Sept 2026 PMID 42762504
- Prognostic impact of diabetes or hypertension in smokers with CRPC receiving enzalutamide or abiraterone. International journal of clinical oncology · 19 Sept 2026 PMID 42762423
- Machine learning and deep learning-based prediction of hypertension and analysis of its major risk factors in Bangladesh. PloS one · 17 Sept 2026 PMID 42752631
- The longitudinal care cascade for hypertension in people with and without HIV in South Africa: A clinic-based observational study. PLoS medicine · 11 Sept 2026 PMID 42726776
- Antihypertensive Medication Patterns in Patients with Hypertension that is Harder to Control: Insights from the EnligHTN Study. Advances in therapy · 11 Sept 2026 PMID 42726373
- "Uncontrolled Hypertension Among Medicare Beneficiaries in Rural South Carolina.". The journals of gerontology. Series A, Biological sciences and medical sciences · 10 Sept 2026 PMID 42720604
- Using Machine Learning to Identify Social Risk Factors of Hypertension and Diabetes in New York City: Evidence to Support the HealthyNYC Initiative. Journal of the American Heart Association · 9 Sept 2026 PMID 42714583
- Sex differences in trajectories to cardio-renal and mental health outcomes following the onset of type 2 diabetes: An observational cohort study using multi-state analysis in the UK Clinical Practice Research Datalink. PLoS medicine · 25 Aug 2026 PMID 42640878
- Validation of Self-Reported Disease History in Korea: A National Health Insurance Cohort Study. Journal of Korean medical science · 11 Aug 2026 PMID 42576717
- Association between the Dietary Approaches to Stop Hypertension (DASH) diet and risk of incident heart failure and heart failure-related death: a UK Biobank cohort study. Open heart · 10 Aug 2026 PMID 42575672
- The role of vascular risk factors in white matter tract microstructure: a multi-cohort study in older adults. Alzheimer's & dementia : the journal of the Alzheimer's Association · 31 Jul 2026 PMID 42535262
- A CVD Classification Model for Individuals With Obesity: Multi-Ethnic Validation Based on Multiple Metabolic Indicators. Obesity (Silver Spring, Md.) · 21 Jul 2026 PMID 42480980
- Metabolic score for insulin resistance and cancer mortality: Effect modification by hypertension in a nationwide cohort study. Medicine · 23 May 2026 PMID 42175442
- Comparing adiposity-related predictors of cardiometabolic disease in two Indigenous Guatemalan municipalities: a cross-sectional receiver operating characteristic analysis. BMJ open · 11 May 2026 PMID 42114861
By study type
Clinical trials (1)
- Prognostic impact of diabetes or hypertension in smokers with CRPC receiving enzalutamide or abiraterone. International journal of clinical oncology · 19 Sept 2026 PMID 42762423
Observational studies and case reports (13)
- Association between Chinese visceral adiposity index and prevalent hypertension among older adults in rural China: A cross-sectional study. Clinical and experimental hypertension (New York, N.Y. : 1993) · 9 Oct 2026 PMID 42853626
- Facial nerve palsy and hypertension; unusual presentation of apparent mineralocorticoid excess (AME) syndrome in a paediatric patient. BMJ case reports · 7 Oct 2026 PMID 42843912
- Hypertension epidemiology and primary care indicators in Portugal: a contemporary nationwide analysis. Blood pressure · 1 Oct 2026 PMID 42822005
- Clinical course and management of adrenal endocrine hypertension: A single-center experience. Endocrine regulations · 19 Sept 2026 PMID 42762504
- Machine learning and deep learning-based prediction of hypertension and analysis of its major risk factors in Bangladesh. PloS one · 17 Sept 2026 PMID 42752631
- The longitudinal care cascade for hypertension in people with and without HIV in South Africa: A clinic-based observational study. PLoS medicine · 11 Sept 2026 PMID 42726776
- Using Machine Learning to Identify Social Risk Factors of Hypertension and Diabetes in New York City: Evidence to Support the HealthyNYC Initiative. Journal of the American Heart Association · 9 Sept 2026 PMID 42714583
- Sex differences in trajectories to cardio-renal and mental health outcomes following the onset of type 2 diabetes: An observational cohort study using multi-state analysis in the UK Clinical Practice Research Datalink. PLoS medicine · 25 Aug 2026 PMID 42640878
- Validation of Self-Reported Disease History in Korea: A National Health Insurance Cohort Study. Journal of Korean medical science · 11 Aug 2026 PMID 42576717
- Association between the Dietary Approaches to Stop Hypertension (DASH) diet and risk of incident heart failure and heart failure-related death: a UK Biobank cohort study. Open heart · 10 Aug 2026 PMID 42575672
- The role of vascular risk factors in white matter tract microstructure: a multi-cohort study in older adults. Alzheimer's & dementia : the journal of the Alzheimer's Association · 31 Jul 2026 PMID 42535262
- Metabolic score for insulin resistance and cancer mortality: Effect modification by hypertension in a nationwide cohort study. Medicine · 23 May 2026 PMID 42175442
- Comparing adiposity-related predictors of cardiometabolic disease in two Indigenous Guatemalan municipalities: a cross-sectional receiver operating characteristic analysis. BMJ open · 11 May 2026 PMID 42114861
Human data, design not indexed (1)
- A CVD Classification Model for Individuals With Obesity: Multi-Ethnic Validation Based on Multiple Metabolic Indicators. Obesity (Silver Spring, Md.) · 21 Jul 2026 PMID 42480980
Unclassified: not yet indexed with MeSH (2)
- Antihypertensive Medication Patterns in Patients with Hypertension that is Harder to Control: Insights from the EnligHTN Study. Advances in therapy · 11 Sept 2026 PMID 42726373
- "Uncontrolled Hypertension Among Medicare Beneficiaries in Rural South Carolina.". The journals of gerontology. Series A, Biological sciences and medical sciences · 10 Sept 2026 PMID 42720604
Written from 17 PubMed abstracts, each one listed by PMID above. Published: 2026-09-13. Last written: 2026-09-21 by GPT. Corrections: 2026-09-26 by GPT. Drafted by language models from published abstracts; not medical advice.