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HIV

Human Immunodeficiency Virus (HIV) is a retrovirus that targets and gradually depletes CD4+ T lymphocytes, the central coordinators of adaptive immune function, leading to progressive immunosuppression and the clinical syndrome of acquired immunodeficiency syndrome (AIDS) when untreated.

Where the papers sit

22 papers from the last 6 months study HIV directly · updated from PubMed 10 Oct 2026

Study type 1 clinical trial · 14 observational · 7 human data

Themes one subject · 1 paradigm shift

Those 22 are all about one subject.

  • HIV Population Health

    Viral suppression, prevention, and long-term health remain the shared focus across this broad clinical literature. Recurring concerns include low-level viremia, latency, drug-resistance mutations, comorbidity, polypharmacy, and prognosis. Prevention and care extend to vaccination, maternal and infant transmission, feeding practices, and marginalized populations. The cluster also includes mental health, autoimmune and hepatic disease, and ocular outcomes without a single unifying mechanistic direction.

    22 papers

PARADIGM SHIFT

Severe illness in people with HIV need not be opportunistic disease

The acute autoimmune hepatitis case in a woman with advanced HIV and the erythrovirus-B19-induced pure red cell aplasia case revealing untreated HIV both challenge the assumption that severe organ injury or cytopenia in HIV is primarily infectious or opportunistic: one was caused by de novo autoimmune hepatitis despite profound immunosuppression, while the other was caused by persistent erythrovirus B19 infection after opportunistic infection and drug toxicity had been excluded 42833839Oct 42154736May. The diagnostic frame therefore shifts toward actively investigating autoimmune and other non-opportunistic causes rather than attributing serious new disease to HIV-related infection by default.

HIV (Human Immunodeficiency Virus)

Papers

The 22 papers from the last 6 months that study HIV directly, newest first, by theme and by study type. Study types come from PubMed publication types and MeSH headings.

By theme

HIV Population Health (22)
  1. Cell heterogeneity contributes to the variable response of HIV-1 to latency-reversing agents. Science advances · 9 Oct 2026 PMID 42853951
  2. A US-Based National Virtual Cohort of People Living With HIV at Risk for Viral Nonsuppression: Protocol for the EPI-LoVE Prospective Cohort Study. JMIR research protocols · 7 Oct 2026 PMID 42842829
  3. Acute autoimmune hepatitis diagnosed concurrently with human immunodeficiency virus. BMJ case reports · 5 Oct 2026 PMID 42833839
  4. Comorbidity and polypharmacy burden among people living with HIV in the United States stratified by age, sex, and race: updated evidence from a contemporary cohort. HIV research & clinical practice · 14 Sept 2026 PMID 42735234
  5. AI for Prognosis Among People Living With HIV: Protocol for a Systematic Review and Meta-Analysis. JMIR research protocols · 18 Aug 2026 PMID 42612074
  6. Influenza vaccination uptake among people living with HIV in Melbourne, 2015-2025: a repeated cross-sectional study. Vaccine · 13 Aug 2026 PMID 42594643
  7. Infant feeding practice and associated factors among hiv-positive mothers attending anti-retroviral therapy services in health facilities of Bahir Dar City. Scientific reports · 6 Aug 2026 PMID 42562836
  8. Weekly HIV pill moves closer but vaccine studies face new questions. Science (New York, N.Y.) · 6 Aug 2026 PMID 42561052
  9. Study Design, Methods, and Modeling in Networks to Inform HIV Interventions and Policy in Marginalized Populations. Rhode Island medical journal (2013) · 25 Jun 2026 PMID 42348626
  10. ENding HIV transmission to infants by Generating Evidence to optimise prevention and care for pregnant and postpartum Adolescent Girls and young women with HIV in Tanzania (ENGAGE): study protocol for a mixed-methods research project. BMJ open · 18 Jun 2026 PMID 42315270
  11. Factors associated with low-level viremia in people living with HIV: A 10-year retrospective study in South Korea. PloS one · 16 Jun 2026 PMID 42302078
  12. A case of transient hepatocellular injury in an HIV monoclonal antibody trial. International journal of STD & AIDS · 6 Jun 2026 PMID 42249623
  13. HIV-1 APOBEC-context Mutations Detected by Next-Generation Sequencing in Plasma: Implications for Drug Resistance Interpretation. The Journal of infectious diseases · 5 Jun 2026 PMID 42244370
  14. Emerging Prevention During the Mpox Outbreak: Associations Between Mpox Vaccination Intent/Uptake, HIV Vaccination Intent, and Mpox Concern Among LGBTQ Adults. AIDS education and prevention : official publication of the International Society for AIDS Education · 1 Jun 2026 PMID 42223400
  15. Expressive writing intervention on optimism and coping modes of newly diagnosed people with human immunodeficiency virus: A randomized controlled trial. Medicine · 30 May 2026 PMID 42216406
  16. Beyond CD4: Posterior segment findings and virologic-immunologic predictors in highly active antiretroviral therapy-naïve HIV patients. Indian journal of ophthalmology · 27 May 2026 PMID 42200741
  17. Impacts of the COVID-19 pandemic on the lives of adolescents living with HIV aged 10-15 years and their families in Vietnam. BMC public health · 27 May 2026 PMID 42192372
  18. Erythrovirus-B19-Induced Pure Red Cell Aplasia Revealing Untreated HIV Infection. The American journal of case reports · 19 May 2026 PMID 42154736
  19. Health-Related Quality of Life in Well-treated People With HIV and Comparators Over an 8-year Period: A Longitudinal Analysis From the Prospective AGEhIV Cohort Study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 14 May 2026 PMID 42133472
  20. Establishment of an intelligent auto-verification system for infectious serological markers in a clinical laboratory from West China. Medicine · 1 May 2026 PMID 42065201
  21. Syphilitic Uveitis in HIV-Positive and -Negative Patients: A Multicenter Cohort Study. Turkish journal of ophthalmology · 27 Apr 2026 PMID 42037575
  22. Who is the expert? A process guide to incorporate lived/living experience into directed acyclic graphs: an applied example from HIV research. Journal of epidemiology and community health · 22 Apr 2026 PMID 42020304

By study type

Clinical trials (1)
  1. Expressive writing intervention on optimism and coping modes of newly diagnosed people with human immunodeficiency virus: A randomized controlled trial. Medicine · 30 May 2026 PMID 42216406
Observational studies and case reports (14)
  1. A US-Based National Virtual Cohort of People Living With HIV at Risk for Viral Nonsuppression: Protocol for the EPI-LoVE Prospective Cohort Study. JMIR research protocols · 7 Oct 2026 PMID 42842829
  2. Acute autoimmune hepatitis diagnosed concurrently with human immunodeficiency virus. BMJ case reports · 5 Oct 2026 PMID 42833839
  3. Comorbidity and polypharmacy burden among people living with HIV in the United States stratified by age, sex, and race: updated evidence from a contemporary cohort. HIV research & clinical practice · 14 Sept 2026 PMID 42735234
  4. Influenza vaccination uptake among people living with HIV in Melbourne, 2015-2025: a repeated cross-sectional study. Vaccine · 13 Aug 2026 PMID 42594643
  5. Infant feeding practice and associated factors among hiv-positive mothers attending anti-retroviral therapy services in health facilities of Bahir Dar City. Scientific reports · 6 Aug 2026 PMID 42562836
  6. Factors associated with low-level viremia in people living with HIV: A 10-year retrospective study in South Korea. PloS one · 16 Jun 2026 PMID 42302078
  7. A case of transient hepatocellular injury in an HIV monoclonal antibody trial. International journal of STD & AIDS · 6 Jun 2026 PMID 42249623
  8. HIV-1 APOBEC-context Mutations Detected by Next-Generation Sequencing in Plasma: Implications for Drug Resistance Interpretation. The Journal of infectious diseases · 5 Jun 2026 PMID 42244370
  9. Emerging Prevention During the Mpox Outbreak: Associations Between Mpox Vaccination Intent/Uptake, HIV Vaccination Intent, and Mpox Concern Among LGBTQ Adults. AIDS education and prevention : official publication of the International Society for AIDS Education · 1 Jun 2026 PMID 42223400
  10. Beyond CD4: Posterior segment findings and virologic-immunologic predictors in highly active antiretroviral therapy-naïve HIV patients. Indian journal of ophthalmology · 27 May 2026 PMID 42200741
  11. Impacts of the COVID-19 pandemic on the lives of adolescents living with HIV aged 10-15 years and their families in Vietnam. BMC public health · 27 May 2026 PMID 42192372
  12. Erythrovirus-B19-Induced Pure Red Cell Aplasia Revealing Untreated HIV Infection. The American journal of case reports · 19 May 2026 PMID 42154736
  13. Health-Related Quality of Life in Well-treated People With HIV and Comparators Over an 8-year Period: A Longitudinal Analysis From the Prospective AGEhIV Cohort Study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 14 May 2026 PMID 42133472
  14. Syphilitic Uveitis in HIV-Positive and -Negative Patients: A Multicenter Cohort Study. Turkish journal of ophthalmology · 27 Apr 2026 PMID 42037575
Human data, design not indexed (7)
  1. Cell heterogeneity contributes to the variable response of HIV-1 to latency-reversing agents. Science advances · 9 Oct 2026 PMID 42853951
  2. AI for Prognosis Among People Living With HIV: Protocol for a Systematic Review and Meta-Analysis. JMIR research protocols · 18 Aug 2026 PMID 42612074
  3. Weekly HIV pill moves closer but vaccine studies face new questions. Science (New York, N.Y.) · 6 Aug 2026 PMID 42561052
  4. Study Design, Methods, and Modeling in Networks to Inform HIV Interventions and Policy in Marginalized Populations. Rhode Island medical journal (2013) · 25 Jun 2026 PMID 42348626
  5. ENding HIV transmission to infants by Generating Evidence to optimise prevention and care for pregnant and postpartum Adolescent Girls and young women with HIV in Tanzania (ENGAGE): study protocol for a mixed-methods research project. BMJ open · 18 Jun 2026 PMID 42315270
  6. Establishment of an intelligent auto-verification system for infectious serological markers in a clinical laboratory from West China. Medicine · 1 May 2026 PMID 42065201
  7. Who is the expert? A process guide to incorporate lived/living experience into directed acyclic graphs: an applied example from HIV research. Journal of epidemiology and community health · 22 Apr 2026 PMID 42020304
bioLLM/wiki is a literature-navigation aid for people who read primary research. It is not a medical resource, and it is not a substitute for a clinician, a pharmacist or the source papers themselves. Because the articles are drafted by language models, they can be incomplete or wrong in ways that read fluently. Please see the editorial policy and medical disclaimer before relying on anything here.

Written from 22 PubMed abstracts, each one listed by PMID above. Published: 2026-08-12. Drafted by language models from published abstracts; not medical advice.