Quality of life
Quality of life (QoL) is a multidimensional clinical metric describing a person’s perceived well-being and ability to function within physical, psychological, social, and role-related domains.
Quality of life (QoL) is a multidimensional clinical metric describing a person’s perceived well-being and ability to function within physical, psychological, social, and role-related domains. In medicine, it is commonly assessed through patient-reported outcomes that capture symptoms, functional capacity, emotional state, social participation, treatment burden, and satisfaction with care. Unlike mortality or survival, QoL reflects how a disease and its management affect the patient’s lived experience.
QoL is influenced by interacting clinical and social factors, including pain, fatigue, anxiety, depression, disability, nutrition, adverse events, treatment adherence, interpersonal support, and disease-related functional limitations. It is therefore used across oncology, rheumatology, neurology, infectious disease, rehabilitation, palliative care, and maternal health. In the supplied literature, QoL is evaluated alongside cancer, chemotherapy, breast cancer, acute stroke, mild cognitive impairment, HIV, rheumatoid arthritis, and musculoskeletal pain. It may serve as a primary outcome, a secondary patient-reported outcome, or one component of broader evaluations that also include survival, mortality, symptom control, caregiver burden, and health-care utilization.
QoL has no single biological mechanism of action because it is an outcome rather than a molecular target. Changes in QoL can reflect the combined effects of disease activity, pain and fatigue, emotional distress, physical function, social support, treatment toxicity, and the patient’s ability to participate in daily activities. Validated QoL instruments are consequently important for comparing interventions whose benefits may not be adequately represented by physiological measurements alone.
- Study protocol of a randomized controlled trial for the effectiveness of psychomotor therapy on quality of life and psychomotor skills in depression. PMID 42717325
Where the papers sit
11 papers study quality of life directly. Those 11 are one subject: Rehabilitation and Supportive Care. Exercise, psychosocial support, dignity therapy, digital reminders and coordinated care are being tested to improve quality of life across cancer, stroke, dementia and rheumatoid arthritis. Patient-reported function, dignity and symptom burden recur as endpoints. No way of splitting those 11 scores better than chance.
Recent Findings on quality of life
Rehabilitation and Supportive Care: Psychomotor therapy, exercise, digital reminders, dignity therapy, and coordinated care target quality of life alongside function or symptom burden across several conditions 42717325Sep42661382Aug42533012Jul42497412Jul42576446Aug42659650Aug42600156Aug. Yoga, combined exercise, Pilates, and SMART4MD improved quality of life or related outcomes, although SMART4MD produced only a modest QoL-AD benefit 42661382Aug42533012Jul42497412Jul. Dignity Therapy reduced emotional and dignity-related distress while quality of life remained stable, and caregiver benefits from SMART4MD were less consistent 42576446Aug42497412Jul. Perceived interpersonal support correlated with greater quality of life during chemotherapy, while studies of cancer pain committees, CASCADE stroke care, psychomotor therapy, medicinal cannabis, and yoga in people living with HIV are extending evaluation toward multidisciplinary and longitudinal care 42647840Aug42659650Aug42600156Aug42717325Sep42476829Jul42044105Apr. Cancer survivors in Tunisia are also being assessed for physical, emotional, and social reintegration and predictors of poor post-remission quality of life 42043618Apr.
Written from 11 PubMed abstracts, each one cited by PMID above. Published: 2026-09-02. Last written: 2026-09-11 by GPT. Drafted by language models from published abstracts; not medical advice.