Pseudomonas aeruginosa
Pseudomonas aeruginosa is a Gram-negative bacterium and a major opportunistic pathogen of clinical importance.
Pseudomonas aeruginosa is a Gram-negative bacterium and a major opportunistic pathogen of clinical importance. It is widely recognized for its intrinsic and acquired antimicrobial resistance, its ability to form biofilms, and its persistence in hospital and community settings. These traits make it a frequent cause of difficult-to-treat infections, particularly in intensive care units, burn and wound infections, chronic lung disease, and other settings where host defenses are compromised.
Biologically, P. aeruginosa is notable for its adaptability to hostile environments, including antibiotic exposure, mechanical confinement, and polymicrobial communities. Recent studies highlighted in the provided contexts emphasize its role as a carbapenem-resistant and multidrug-resistant pathogen, its involvement in chronic cystic fibrosis lung infection, and its capacity to co-colonize with organisms such as Staphylococcus aureus, Candida albicans, Escherichia coli, Acinetobacter baumannii, and Haemophilus influenzae. Because of these features, it is a major target for research into biofilm disruption, quorum sensing inhibition, novel antimicrobials, wound dressings, nanomaterials, and improved diagnostic assays.
Where the papers sit
25 papers from the last 6 months study pseudomonas aeruginosa directly · updated from PubMed 12 Oct 2026
Study type 0 clinical trials · 1 observational · 2 human data · 20 preclinical · 2 unclassified
Themes one subject
Those 25 are all about one subject.
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Antimicrobial Infection Management
Antimicrobial infection management is broadening beyond conventional antibiotics toward photodynamic therapy, essential oils, phytochemicals, probiotics, and antibacterial nanoparticles. Wound infection and sepsis remain the main clinical settings, with diabetic wounds, polymicrobial disease, and multidrug resistance recurring across studies. Rapid detection is advancing through spectroscopic classification and multiplex immunoassays, while animal models support preclinical testing. Antibiotic tolerance and environmental effects such as confinement or light exposure remain important barriers.
Papers
The 25 papers from the last 6 months that study pseudomonas aeruginosa directly, newest first, by theme and by study type. Study types come from PubMed publication types and MeSH headings.
By theme
Antimicrobial Infection Management (25)
- PMID 41936120
- PMID 41934629
- Highly Efficient Photodynamic Inactivation of Multidrug-resistant Pseudomonas aeruginosa, Staphylococcus aureus and Acinetobacter baumannii Strains by Toluidine Blue-graphene Oxide Quantum Dot/Ag Nanoparticle Conjugate. Current microbiology · 6 Sept 2026 PMID 42701925
- In Silico and In Vitro Evaluation of Atriplex halimus: Antibacterial Activity, Molecular Docking, ADMET Profiling, and Cytotoxicity Assessment. Chemistry & biodiversity · 31 Aug 2026 PMID 42673104
- Prevalence and associated risk factors of Pseudomonas aeruginosa infection in Diabetic wounds in Duhok province, Iraq. PloS one · 24 Jul 2026 PMID 42497179
- Delivery of a functional sugar-induced probiotic secretome against polymicrobial bacterial infection. Materials horizons · 20 Jul 2026 PMID 42474373
- Goldenberry (Physalis peruviana L.) juice inhibits foodborne pathogens while promoting probiotic bacterial growth. Scientific reports · 16 Jul 2026 PMID 42463768
- Spectroscopic discrimination of bacterial species of variable pathogenicity through explainable machine learning. Nanoscale · 9 Jul 2026 PMID 42422903
- Chemical fingerprints of Lamiaceae essential oils: targeting biofilm viability, biomass, metabolic activity, and membrane integrity. Biofouling · 23 Jun 2026 PMID 42332877
- Near-infrared-triggered synergistic therapy with a Ru-based nanocomposite hydrogel for eradicating multidrug-resistant wound infections. Journal of materials chemistry. B · 16 Jun 2026 PMID 42300215
- Biosynthesis of ecofriendly antibacterial nanoparticles with healing effects in a murine diabetic skin infection model. Scientific reports · 15 Jun 2026 PMID 42297939
- Development and validation of a rabbit model of Pseudomonas aeruginosa hyperdynamic septic shock for preclinical drug development. Antimicrobial agents and chemotherapy · 15 Jun 2026 PMID 42295241
- Machine Learning-Assisted Surface Ligand Engineering Strategy for Enhanced Sensitivity of Immunoassay Platform. Analytical chemistry · 5 Jun 2026 PMID 42246701
- Ultra-Stable 2D Magneto-Fluorescent Probe-Mediated Multiplex Immunochromatographic Assay for Precise Bedside Detection of Sepsis. ACS nano · 4 Jun 2026 PMID 42237556
- Programmable core-shell microneedles with marine chondroitin sulfate core and chito-oligosaccharide shell disrupt the pathological microenvironment cycle for enhanced healing of infected burn wounds. International journal of biological macromolecules · 3 Jun 2026 PMID 42235776
- Copper ions restore antibacterial activity of tigecycline by regulating photodegradation pathway under light exposure‌. Communications biology · 29 May 2026 PMID 42215682
- Growth in confinement promotes Pseudomonas aeruginosa tolerance to antibiotics. Proceedings of the National Academy of Sciences of the United States of America · 29 May 2026 PMID 42213750
- Phytochemical signatures and multifunctional bioactivities of two Ocimum basilicum varieties (Obb vs. Obg): antimicrobial, antioxidant, and anticancer potential. Scientific reports · 25 May 2026 PMID 42185519
- Design, synthesis and antibacterial evaluation of novel unsaturated butenolide-fatty amine hybrids against multidrug-resistant pathogens. Bioorganic & medicinal chemistry letters · 21 May 2026 PMID 42167554
- Green Antibacterial-Antioxidant Hydrogel for Infected Wound Healing: Tea Polyphenol and Biosynthesized Silver Nanoparticles in a Deacetylated Sphingan WL Matrix. ACS applied materials & interfaces · 8 May 2026 PMID 42100849
- AI-guided 3D bioprinting of multi-drug-loaded chitosan methacrylate hydrogels for personalized diabetic ulcer repair. Journal of controlled release : official journal of the Controlled Release Society · 7 May 2026 PMID 42097229
- Triple-Responsive Hydrogel Integrating Polyphenol-Metal Activity for Infected Diabetic Wound Therapy. ACS applied materials & interfaces · 5 May 2026 PMID 42084863
- Multi-omics profiling of fungal balls in chronic pulmonary aspergillosis patients reveals microbiome dynamics and metabolic adaptations. mBio · 5 May 2026 PMID 42084394
- Antimicrobial potency and biocompatibility of biogenic selenium nanoparticles by Prosopis farcta. Microbial pathogenesis · 22 Apr 2026 PMID 42019771
- Discovery of BI-10: An Unexplored Broad-Spectrum Antimicrobial Benzimidazole Derivative Targeting Bacterial Membrane. Chembiochem : a European journal of chemical biology · 21 Apr 2026 PMID 42011055
By study type
Observational studies and case reports (1)
- Prevalence and associated risk factors of Pseudomonas aeruginosa infection in Diabetic wounds in Duhok province, Iraq. PloS one · 24 Jul 2026 PMID 42497179
Human data, design not indexed (2)
- Machine Learning-Assisted Surface Ligand Engineering Strategy for Enhanced Sensitivity of Immunoassay Platform. Analytical chemistry · 5 Jun 2026 PMID 42246701
- Ultra-Stable 2D Magneto-Fluorescent Probe-Mediated Multiplex Immunochromatographic Assay for Precise Bedside Detection of Sepsis. ACS nano · 4 Jun 2026 PMID 42237556
Preclinical: animal, cell and lab studies (20)
- Highly Efficient Photodynamic Inactivation of Multidrug-resistant Pseudomonas aeruginosa, Staphylococcus aureus and Acinetobacter baumannii Strains by Toluidine Blue-graphene Oxide Quantum Dot/Ag Nanoparticle Conjugate. Current microbiology · 6 Sept 2026 PMID 42701925
- In Silico and In Vitro Evaluation of Atriplex halimus: Antibacterial Activity, Molecular Docking, ADMET Profiling, and Cytotoxicity Assessment. Chemistry & biodiversity · 31 Aug 2026 PMID 42673104
- Photodynamic anti-biofilm PHEMA/Rose Bengal hydrogels enhanced by iodide: evidence for hydrogen peroxide and triiodide formation. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 24 Aug 2026 PMID 42635957
- AS04-adjuvanted semisynthetic glycoconjugate vaccine against Pseudomonas aeruginosa. Vaccine · 19 Aug 2026 PMID 42617357
- Delivery of a functional sugar-induced probiotic secretome against polymicrobial bacterial infection. Materials horizons · 20 Jul 2026 PMID 42474373
- Goldenberry (Physalis peruviana L.) juice inhibits foodborne pathogens while promoting probiotic bacterial growth. Scientific reports · 16 Jul 2026 PMID 42463768
- Spectroscopic discrimination of bacterial species of variable pathogenicity through explainable machine learning. Nanoscale · 9 Jul 2026 PMID 42422903
- Chemical fingerprints of Lamiaceae essential oils: targeting biofilm viability, biomass, metabolic activity, and membrane integrity. Biofouling · 23 Jun 2026 PMID 42332877
- Near-infrared-triggered synergistic therapy with a Ru-based nanocomposite hydrogel for eradicating multidrug-resistant wound infections. Journal of materials chemistry. B · 16 Jun 2026 PMID 42300215
- Biosynthesis of ecofriendly antibacterial nanoparticles with healing effects in a murine diabetic skin infection model. Scientific reports · 15 Jun 2026 PMID 42297939
- Development and validation of a rabbit model of Pseudomonas aeruginosa hyperdynamic septic shock for preclinical drug development. Antimicrobial agents and chemotherapy · 15 Jun 2026 PMID 42295241
- Programmable core-shell microneedles with marine chondroitin sulfate core and chito-oligosaccharide shell disrupt the pathological microenvironment cycle for enhanced healing of infected burn wounds. International journal of biological macromolecules · 3 Jun 2026 PMID 42235776
- Growth in confinement promotes Pseudomonas aeruginosa tolerance to antibiotics. Proceedings of the National Academy of Sciences of the United States of America · 29 May 2026 PMID 42213750
- Phytochemical signatures and multifunctional bioactivities of two Ocimum basilicum varieties (Obb vs. Obg): antimicrobial, antioxidant, and anticancer potential. Scientific reports · 25 May 2026 PMID 42185519
- Design, synthesis and antibacterial evaluation of novel unsaturated butenolide-fatty amine hybrids against multidrug-resistant pathogens. Bioorganic & medicinal chemistry letters · 21 May 2026 PMID 42167554
- Green Antibacterial-Antioxidant Hydrogel for Infected Wound Healing: Tea Polyphenol and Biosynthesized Silver Nanoparticles in a Deacetylated Sphingan WL Matrix. ACS applied materials & interfaces · 8 May 2026 PMID 42100849
- AI-guided 3D bioprinting of multi-drug-loaded chitosan methacrylate hydrogels for personalized diabetic ulcer repair. Journal of controlled release : official journal of the Controlled Release Society · 7 May 2026 PMID 42097229
- Triple-Responsive Hydrogel Integrating Polyphenol-Metal Activity for Infected Diabetic Wound Therapy. ACS applied materials & interfaces · 5 May 2026 PMID 42084863
- Antimicrobial potency and biocompatibility of biogenic selenium nanoparticles by Prosopis farcta. Microbial pathogenesis · 22 Apr 2026 PMID 42019771
- Discovery of BI-10: An Unexplored Broad-Spectrum Antimicrobial Benzimidazole Derivative Targeting Bacterial Membrane. Chembiochem : a European journal of chemical biology · 21 Apr 2026 PMID 42011055
Unclassified: not yet indexed with MeSH (2)
- Copper ions restore antibacterial activity of tigecycline by regulating photodegradation pathway under light exposure‌. Communications biology · 29 May 2026 PMID 42215682
- Multi-omics profiling of fungal balls in chronic pulmonary aspergillosis patients reveals microbiome dynamics and metabolic adaptations. mBio · 5 May 2026 PMID 42084394
Written from 25 PubMed abstracts, each one listed by PMID above. Published: 2026-07-01. Last written: 2026-09-08 by GPT. Drafted by language models from published abstracts; not medical advice.