Automated Insulin Delivery
Automated insulin delivery (AID) is a diabetes therapy that combines a continuous glucose monitor, an insulin pump, and a control algorithm to adjust insulin delivery in response to measured glucose.
Automated insulin delivery (AID) is a diabetes therapy that combines a continuous glucose monitor, an insulin pump, and a control algorithm to adjust insulin delivery in response to measured glucose. By automating aspects of insulin dosing, AID is intended to support glycemic control while limiting exposure to hypoglycemia. Systems may use tubed or disposable tubeless insulin pumps and may incorporate adaptive algorithms, including technologies studied with Control-IQ and Omnipod 5 Automated Insulin Delivery System. AID is used particularly in type 1 diabetes, where its effects are assessed using measures such as hemoglobin A1c, time-in-range 70–180 mg/dL, mean glucose, and severe hypoglycemia.
Current research examines AID in children and adolescents as well as adults, including comparisons with Multiple Daily Injections and sensor-augmented pump therapy. Studies also evaluate postprandial control according to meal composition, treatment satisfaction, diabetes distress, device adoption and discontinuation, and diabetes-related acute care utilization. Emerging applications include people with cystic fibrosis-related diabetes and advanced chronic kidney disease, populations in which feasibility, safety, insulin dose, and durability of glycemic benefit require specific evaluation.
Where the papers sit
11 papers from the last 6 months study Automated Insulin Delivery directly · updated from PubMed 1 Nov 2026
Study type 1 clinical trial · 7 observational · 3 human data
Themes 3 themes
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AID in Diverse Diabetes Care
AID is being tested across settings where standard glucose management is difficult, including advanced chronic kidney disease and cystic-fibrosis-related diabetes. Other work follows device adoption, discontinuation, acute-care use, and diabetes distress in adults with type 1 diabetes. Comparisons with non-users and mixed-methods accounts broaden the endpoints beyond glucose metrics. The shared direction is implementation in diverse populations, while clinical advantages and barriers remain context-dependent.
5 papers · 45.5%
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Real-World Glycemic Control
Time-in-range is the central outcome, with attention to time below range, hemoglobin A1c, and safety across routine care. Adaptive tubeless systems and open-source AID are evaluated in children and across age groups, while Control-IQ studies test how meal composition alters postprandial control. Menstrual-cycle changes in insulin requirements highlight the need for context-sensitive settings. The work favors real-world personalization rather than a single universal algorithm.
4 papers · 36.4%
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Youth AID Adoption and Outcomes
Predicting who benefits after AID initiation is the main focus, using glycemic trajectories, hemoglobin A1c, and logistic models. Youth studies seek clinical features that distinguish improving from less-improving trajectories. Multicenter data in preschool children extend AID evaluation to early use, where safety and feasibility remain central. The evidence supports risk-stratified counseling, but does not establish a single predictor of success.
2 papers · 18.2%
Papers
The 11 papers from the last 6 months that study Automated Insulin Delivery directly, newest first, by theme and by study type. Study types come from PubMed publication types and MeSH headings.
By theme
AID in Diverse Diabetes Care (5)
- Comparison of AID users and non-users regarding glycemic control and diabetes distress: A mixed-methods study. PloS one · 24 Jul 2026 PMID 42497120
- Diabetes-related acute care utilization following initiation of automated insulin delivery (AID): A comparison of a disposable tubeless AID system and durable tubed systems. Journal of managed care & specialty pharmacy · 9 Jul 2026 PMID 42424112
- Advancing Cystic Fibrosis-Related Diabetes Care With Automated Insulin Delivery Systems. Clinical therapeutics · 16 Jun 2026 PMID 42303551
- Adopters and discontinuers: Mapping the diabetes device adoption journeys of adults with type 1 diabetes after continuous glucose monitoring uptake. Patient education and counseling · 28 May 2026 PMID 42208318
- The impact of automated insulin delivery on glucose management in people with diabetes and advanced chronic kidney disease. Diabetologia · 10 May 2026 PMID 42108331
Real-World Glycemic Control (4)
- Menstrual cycle-related variations in insulin requirements and glycemic control during automated insulin delivery in adolescents with type 1 diabetes. Journal of pediatric endocrinology & metabolism : JPEM · 28 Aug 2026 PMID 42665003
- Real-World Glycemic Outcomes of Open-Source Automated Insulin Delivery During 12 Months Among People With Type 1 Diabetes Across Age Groups. Diabetes, obesity & metabolism · 27 Aug 2026 PMID 42660857
- Real-World Effectiveness and Safety of a Tubeless Automated Insulin Delivery System With an Adaptive Control Algorithm (APGO) in Children and Adolescents With Type 1 Diabetes: A Multicentre Observational Study. Diabetes, obesity & metabolism · 23 Jul 2026 PMID 42488981
- Postprandial Glycemic Control With Automated Insulin Delivery With Control-IQ Technology: The Impact of Meal Composition. Diabetes, obesity & metabolism · 20 Jul 2026 PMID 42476949
Youth AID Adoption and Outcomes (2)
- What Makes the Difference? Predicting Glycemic Trajectories Following Initiation of Automated Insulin Delivery Systems in Youth With Type 1 Diabetes. Diabetes care · 16 Jul 2026 PMID 42461939
- Automated Insulin Delivery Use Among Preschool-Age Children With Type 1 Diabetes: A T1D Exchange Multicenter Analysis. Journal of diabetes science and technology · 23 Jun 2026 PMID 42335144
By study type
Clinical trials (1)
- The impact of automated insulin delivery on glucose management in people with diabetes and advanced chronic kidney disease. Diabetologia · 10 May 2026 PMID 42108331
Observational studies and case reports (7)
- Menstrual cycle-related variations in insulin requirements and glycemic control during automated insulin delivery in adolescents with type 1 diabetes. Journal of pediatric endocrinology & metabolism : JPEM · 28 Aug 2026 PMID 42665003
- Real-World Effectiveness and Safety of a Tubeless Automated Insulin Delivery System With an Adaptive Control Algorithm (APGO) in Children and Adolescents With Type 1 Diabetes: A Multicentre Observational Study. Diabetes, obesity & metabolism · 23 Jul 2026 PMID 42488981
- Postprandial Glycemic Control With Automated Insulin Delivery With Control-IQ Technology: The Impact of Meal Composition. Diabetes, obesity & metabolism · 20 Jul 2026 PMID 42476949
- Diabetes-related acute care utilization following initiation of automated insulin delivery (AID): A comparison of a disposable tubeless AID system and durable tubed systems. Journal of managed care & specialty pharmacy · 9 Jul 2026 PMID 42424112
- Automated Insulin Delivery Use Among Preschool-Age Children With Type 1 Diabetes: A T1D Exchange Multicenter Analysis. Journal of diabetes science and technology · 23 Jun 2026 PMID 42335144
- Advancing Cystic Fibrosis-Related Diabetes Care With Automated Insulin Delivery Systems. Clinical therapeutics · 16 Jun 2026 PMID 42303551
- Adopters and discontinuers: Mapping the diabetes device adoption journeys of adults with type 1 diabetes after continuous glucose monitoring uptake. Patient education and counseling · 28 May 2026 PMID 42208318
Human data, design not indexed (3)
- Real-World Glycemic Outcomes of Open-Source Automated Insulin Delivery During 12 Months Among People With Type 1 Diabetes Across Age Groups. Diabetes, obesity & metabolism · 27 Aug 2026 PMID 42660857
- Comparison of AID users and non-users regarding glycemic control and diabetes distress: A mixed-methods study. PloS one · 24 Jul 2026 PMID 42497120
- What Makes the Difference? Predicting Glycemic Trajectories Following Initiation of Automated Insulin Delivery Systems in Youth With Type 1 Diabetes. Diabetes care · 16 Jul 2026 PMID 42461939
Written from 11 PubMed abstracts, each one listed by PMID above. Published: 2026-10-02. Drafted by language models from published abstracts; not medical advice.