Uric acid

Where the papers sit

13 papers from the last 6 months study uric acid directly · updated from PubMed 7 Oct 2026

• Clinical Uric Acid Assessment

  Uric acid ratios are being tested as accessible markers for Parkinson’s disease, protein-energy wasting, and severe obstructive sleep apnea. The studies emphasize associations with oxidative inflammation, intact parathyroid hormone, hypertension, diabetes, and blood-cell indices rather than causal effects. In parallel, digital twins and high-throughput mass spectrometry aim to make uric acid prediction or measurement more personalized and scalable. Evidence remains heterogeneous, with clinical utility still needing prospective validation.

  5 papers · 38.5%

• Gut Microbiota and Obesity

  Hyperuricemia is being linked to gut microbial remodeling, increased dietary lipid absorption, and obesity through liver–gut signaling. Microbiota and metabolomic changes recur alongside altered short-chain fatty acid metabolism. The work is moving toward mechanistic links between uric acid, intestinal nutrient handling, and systemic inflammation. Gut–pancreas dysregulation and CNR1 signaling extend this framework beyond obesity to acute pancreatitis.

  4 papers · 30.8%

• Nanomaterial Uric Acid Biosensors

  Uric acid detection is moving toward ultrasensitive, selective platforms built from magnetic nanoparticles, quantum dots, graphene, and plasmonic metal-organic frameworks. Chemiluminescent, electrochemical, SERS, and fluorescent designs target low detection limits in solution or urinary samples. Several platforms support multiplexing with glucose or cholesterol, while non-enzymatic sensing seeks greater stability. Selectivity, practical sample testing, and translation beyond proof-of-concept remain open challenges.

  4 papers · 30.8%