Liver transplantation

Where the papers sit

15 papers from the last 6 months study liver transplantation directly · updated from PubMed 2 Nov 2026

• Liver Transplant Indications and Outcomes

  Liver transplantation is examined across access, indication, perioperative risk and long-term outcomes rather than around one disease. HCC studies address evaluation, recurrence-free survival and projected surgical capacity, while ACLF work emphasizes the patient’s initial trajectory. Pediatric and rare indications include biliary atresia, gestational alloimmune liver disease and erythropoietic protoporphyria. Other papers address HBV-HDV transmission, 30-day mortality and preparation for surgery, with no single therapeutic direction emerging.

  9 papers · 60%

• Machine Perfusion and Graft Survival

  Normothermic regional and ex situ machine perfusion are being compared with hypothermic oxygenated perfusion to preserve and assess marginal donor livers. Real-world cohorts focus on graft survival and the practical expansion of donation after circulatory death. National practice patterns increasingly treat regional and ex situ approaches as complementary rather than mutually exclusive. Out-of-hours transplantation adds an operational question, linking timing of surgery to post-transplant outcomes.

  3 papers · 20%

• Perioperative Transplant Care

  Acute kidney injury is the main recurring concern, with retrospective risk-factor analysis and machine-learning nomograms aimed at earlier postoperative prediction. Multivariable logistic regression links risk to perioperative timing and clinical factors, but external validation remains limited. A separate technical strand focuses on bile duct anastomosis, emphasizing reproducible strategies as surgeons progress from novice to mastery. The cluster therefore centers on reducing surgical morbidity through risk stratification and technical standardization.

  3 papers · 20%