Klebsiella pneumoniae
Klebsiella pneumoniae is a Gram-negative, encapsulated bacterium in the family Enterobacteriaceae and a clinically important opportunistic pathogen.
Klebsiella pneumoniae is a Gram-negative, encapsulated bacterium in the family Enterobacteriaceae and a clinically important opportunistic pathogen. It is best known for causing healthcare-associated and community-acquired infections, including pneumonia, bloodstream infection, urinary tract infection, and other invasive infections, particularly in individuals with underlying illness or impaired host defenses. Its pathogenic success is supported by traits such as capsule production, adherence, and the ability to form biofilms, all of which can contribute to persistence in host tissues and on medical devices.
From a biomedical perspective, Klebsiella pneumoniae is also a major target in antimicrobial resistance research. It is frequently studied alongside related pathogens such as Acinetobacter baumannii, Pseudomonas aeruginosa, Staphylococcus aureus, and Escherichia coli because it can acquire resistance to β-lactam antibiotic classes, including carbapenems and piperacillin-tazobactam. Recent work has focused on rapid detection methods, mechanistic studies of resistance and immune evasion, and anti-biofilm or antimicrobial approaches designed to suppress multidrug-resistant strains.
Where the papers sit
9 papers from the last 6 months study klebsiella pneumoniae directly · updated from PubMed 10 Oct 2026
Study type 0 clinical trials · 1 human data · 8 preclinical
Themes one subject
Those 9 are all about one subject.
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Alternative Antimicrobial Strategies
Multidrug-resistant Klebsiella pneumoniae is being addressed with alternatives to conventional antibiotics, including nanoemulsions, selenium and zinc oxide nanoparticles, antimicrobial peptides, essential oils, and rifampicin-loaded exosomes. Recurrent targets are efflux pumps, virulence factors, biofilms, oxygen consumption, and inflammation. Spectroscopic machine learning adds rapid species discrimination, while molecular profiling tracks antibiotic responses. The approaches remain preclinical and heterogeneous, with efficacy and toxicity requiring further comparison.
Papers
The 9 papers from the last 6 months that study klebsiella pneumoniae directly, newest first, by theme and by study type. Study types come from PubMed publication types and MeSH headings.
By theme
Alternative Antimicrobial Strategies (9)
- PMID 41921827
- Phenotypic and molecular detection of efflux pump and expression profiling genes in Klebsiella pneumoniae exposed to ciprofloxacin and amoxicillin/clavulanic acid. Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2 Sept 2026 PMID 42684540
- Nanoemulsion-Mediated Suppression of Multidrug-Resistant Klebsiella pneumoniae via Oxygen Consumption Reduction and Biofilm Inhibition. Current microbiology · 30 Jul 2026 PMID 42530666
- Spectroscopic discrimination of bacterial species of variable pathogenicity through explainable machine learning. Nanoscale · 9 Jul 2026 PMID 42422903
- Co-encapsulation of formic acid and Satureja hortensis essential oil enhances antibacterial and anti-inflammatory activities against Salmonella enterica. Journal of microbiological methods · 16 Jun 2026 PMID 42302970
- ADMCs-derived exosomal vesicles encapsulated with rifampicin to attenuate Klebsiella pneumonia-induced pediatric lung inflammation: In-vitro and In vivo studies. Microbial pathogenesis · 10 Jun 2026 PMID 42269980
- The role of biosynthesized zinc oxide nanoparticles in modulating the expression of virulence factors in multidrug-resistant Klebsiellapneumoniae. Microbial pathogenesis · 10 Jun 2026 PMID 42269978
- Design, synthesis and antibacterial evaluation of novel unsaturated butenolide-fatty amine hybrids against multidrug-resistant pathogens. Bioorganic & medicinal chemistry letters · 21 May 2026 PMID 42167554
- Facile green synthesis of selenium nanoparticles using olive (Olea europaea) leaf extract and their antimicrobial and antibiofilm properties. Scientific reports · 16 May 2026 PMID 42143081
By study type
Human data, design not indexed (1)
- Phenotypic and molecular detection of efflux pump and expression profiling genes in Klebsiella pneumoniae exposed to ciprofloxacin and amoxicillin/clavulanic acid. Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2 Sept 2026 PMID 42684540
Preclinical: animal, cell and lab studies (8)
- Nanoemulsion-Mediated Suppression of Multidrug-Resistant Klebsiella pneumoniae via Oxygen Consumption Reduction and Biofilm Inhibition. Current microbiology · 30 Jul 2026 PMID 42530666
- Programmable macrophage interface engineering enables targeted antibacterial therapy in immunosuppressed infections. Science bulletin · 15 Jul 2026 PMID 42457472
- Spectroscopic discrimination of bacterial species of variable pathogenicity through explainable machine learning. Nanoscale · 9 Jul 2026 PMID 42422903
- Co-encapsulation of formic acid and Satureja hortensis essential oil enhances antibacterial and anti-inflammatory activities against Salmonella enterica. Journal of microbiological methods · 16 Jun 2026 PMID 42302970
- ADMCs-derived exosomal vesicles encapsulated with rifampicin to attenuate Klebsiella pneumonia-induced pediatric lung inflammation: In-vitro and In vivo studies. Microbial pathogenesis · 10 Jun 2026 PMID 42269980
- The role of biosynthesized zinc oxide nanoparticles in modulating the expression of virulence factors in multidrug-resistant Klebsiellapneumoniae. Microbial pathogenesis · 10 Jun 2026 PMID 42269978
- Design, synthesis and antibacterial evaluation of novel unsaturated butenolide-fatty amine hybrids against multidrug-resistant pathogens. Bioorganic & medicinal chemistry letters · 21 May 2026 PMID 42167554
- Facile green synthesis of selenium nanoparticles using olive (Olea europaea) leaf extract and their antimicrobial and antibiofilm properties. Scientific reports · 16 May 2026 PMID 42143081
Written from 9 PubMed abstracts, each one listed by PMID above. Published: 2026-08-15. Last written: 2026-09-04 by GPT. Drafted by language models from published abstracts; not medical advice.