W
bioLLM/wiki

AI-Curated Biotech/Medical Knowledge Base
Live
Back to List View Graph View

Silver nanoparticles

Silver nanoparticles (AgNPs) are nanoscale silver materials investigated in biomedical research for antimicrobial and other biological applications.

Where the papers sit

12 papers from the last 6 months study silver nanoparticles directly · updated from PubMed 1 Nov 2026

Study type 0 clinical trials · 2 human data · 10 preclinical

Themes one subject · 1 paradigm shift

Those 12 are all about one subject.

  • Biomedical Uses and Safety

    Green and bioinspired synthesis recurs across antimicrobial, antifungal, antiparasitic, antidiabetic, reproductive, and wound-focused applications. Plant, fungal, algal, and bacterial products generate particles or combine them with hydrogels, essential oils, photosensitizers, or extracts. Endpoints include pathogen inhibition, sperm parameters, broiler performance, glucose control, and route- and sex-dependent toxicity. The cluster is broad, with no consistent therapeutic direction or settled safety profile.

    12 papers

PARADIGM SHIFT

Silver nanoparticles are not reliable standalone antimicrobials

The donkey-semen storage study and the PEGDA/gelatin hybrid-hydrogel photodynamic-therapy study independently show that treating silver nanoparticles as sufficient antimicrobial agents fails in different systems. In donkey semen, bactericidal concentrations caused dose- and time-dependent sperm toxicity, reducing motility and membrane integrity while increasing reactive oxygen species; in the hydrogel model, silver nanoparticles alone were insufficient for robust bacterial killing, whereas combining them with light-activated photosensitizers produced marked inactivation of Escherichia coli and Staphylococcus aureus 42816940Oct 42155357May. The result is a reversal of the standalone-antimicrobial premise: effective use may require either a compatible delivery context or a complementary antimicrobial mechanism, rather than simply increasing nanoparticle exposure.

Papers

The 12 papers from the last 6 months that study silver nanoparticles directly, newest first, by theme and by study type. Study types come from PubMed publication types and MeSH headings.

By theme

Biomedical Uses and Safety (12)
  1. Eco-friendly biosynthesis of silver nanoparticles by saprophytic Fusarium solani as a sustainable therapeutic approach for the management of methicillin-resistant Staphylococcus aureus wound infections. Microbial cell factories · 18 Oct 2026 PMID 42892689
  2. Bioinspired silver nanoparticles from Barleria lawii leaf extract: phytochemical-mediated synthesis, characterization, and multifunctional properties. Die Naturwissenschaften · 12 Oct 2026 PMID 42862357
  3. Experimental characterization of Pleurotus tuber-regium-derived silver nanoparticles and antifungal activity against Aspergillus fumigatus, Cryptococcus neoformans, and Candida albicans. Archives of microbiology · 10 Oct 2026 PMID 42859228
  4. Silver Nanoparticles in Donkey Semen Stored at 17°C: Effect on Sperm Parameters and Bacterial Growth. Reproduction in domestic animals = Zuchthygiene · 1 Oct 2026 PMID 42816940
  5. Stage-Adaptive Polymeric Platforms: Design of an Alginate/CMC Hydrogel Co-Loaded With Silver Nanoparticles and α-Pinene-Rich Essential Oil for Wound Regeneration. Journal of biomedical materials research. Part B, Applied biomaterials · 26 Sept 2026 PMID 42798198
  6. Efficacy of Vitis vinifera leaf extract and its biosynthesized silver nanoparticles against Eimeria tenella in broilers: Effects on performance, anticoccidial indices, and cecal integrity. Poultry science · 9 Sept 2026 PMID 42715742
  7. Route- and sex-dependent toxicity of clinical-stage silver nanoparticles in mice. Nanoscale · 7 Sept 2026 PMID 42703674
  8. Comparative antidiabetic effects of Cymbopogon citratus leaf extract, derived silver nanoparticles, and their combination in alloxan-induced diabetic mice. Biochemical and biophysical research communications · 6 Sept 2026 PMID 42702151
  9. Bioactive streptomyces-derived silver nanoparticles enhance antibacterial activity against cephalosporin-resistant Escherichia coli and Klebsiella through membrane disruption and in vivo efficacy. Microbial pathogenesis · 25 Aug 2026 PMID 42641969
  10. Biosynthesized silver nanoparticles from Gelediella acerosa as a potent antibacterial agent against Multidrug-resistant wound isolates. Microbial pathogenesis · 24 Aug 2026 PMID 42636915
  11. Green Synthesis of Silver Nanoparticles Using the Extract of Adenosma caeruleum R.Br.: Evaluation of Antibacterial, Antifungal and Antioxidant Activity. Applied biochemistry and biotechnology · 6 Jul 2026 PMID 42406010
  12. Synergistic effects of ionic photosensitizers and silver nanoparticles in PEGDA/gelatin hybrid hydrogels for advanced antibacterial photodynamic therapy. Biomaterials advances · 19 May 2026 PMID 42155357

By study type

Human data, design not indexed (2)
  1. Bioinspired silver nanoparticles from Barleria lawii leaf extract: phytochemical-mediated synthesis, characterization, and multifunctional properties. Die Naturwissenschaften · 12 Oct 2026 PMID 42862357
  2. Biosynthesized silver nanoparticles from Gelediella acerosa as a potent antibacterial agent against Multidrug-resistant wound isolates. Microbial pathogenesis · 24 Aug 2026 PMID 42636915
Preclinical: animal, cell and lab studies (10)
  1. Eco-friendly biosynthesis of silver nanoparticles by saprophytic Fusarium solani as a sustainable therapeutic approach for the management of methicillin-resistant Staphylococcus aureus wound infections. Microbial cell factories · 18 Oct 2026 PMID 42892689
  2. Experimental characterization of Pleurotus tuber-regium-derived silver nanoparticles and antifungal activity against Aspergillus fumigatus, Cryptococcus neoformans, and Candida albicans. Archives of microbiology · 10 Oct 2026 PMID 42859228
  3. Silver Nanoparticles in Donkey Semen Stored at 17°C: Effect on Sperm Parameters and Bacterial Growth. Reproduction in domestic animals = Zuchthygiene · 1 Oct 2026 PMID 42816940
  4. Stage-Adaptive Polymeric Platforms: Design of an Alginate/CMC Hydrogel Co-Loaded With Silver Nanoparticles and α-Pinene-Rich Essential Oil for Wound Regeneration. Journal of biomedical materials research. Part B, Applied biomaterials · 26 Sept 2026 PMID 42798198
  5. Efficacy of Vitis vinifera leaf extract and its biosynthesized silver nanoparticles against Eimeria tenella in broilers: Effects on performance, anticoccidial indices, and cecal integrity. Poultry science · 9 Sept 2026 PMID 42715742
  6. Route- and sex-dependent toxicity of clinical-stage silver nanoparticles in mice. Nanoscale · 7 Sept 2026 PMID 42703674
  7. Comparative antidiabetic effects of Cymbopogon citratus leaf extract, derived silver nanoparticles, and their combination in alloxan-induced diabetic mice. Biochemical and biophysical research communications · 6 Sept 2026 PMID 42702151
  8. Bioactive streptomyces-derived silver nanoparticles enhance antibacterial activity against cephalosporin-resistant Escherichia coli and Klebsiella through membrane disruption and in vivo efficacy. Microbial pathogenesis · 25 Aug 2026 PMID 42641969
  9. Green Synthesis of Silver Nanoparticles Using the Extract of Adenosma caeruleum R.Br.: Evaluation of Antibacterial, Antifungal and Antioxidant Activity. Applied biochemistry and biotechnology · 6 Jul 2026 PMID 42406010
  10. Synergistic effects of ionic photosensitizers and silver nanoparticles in PEGDA/gelatin hybrid hydrogels for advanced antibacterial photodynamic therapy. Biomaterials advances · 19 May 2026 PMID 42155357
bioLLM/wiki is a literature-navigation aid for people who read primary research. It is not a medical resource, and it is not a substitute for a clinician, a pharmacist or the source papers themselves. Because the articles are drafted by language models, they can be incomplete or wrong in ways that read fluently. Please see the editorial policy and medical disclaimer before relying on anything here.

Written from 12 PubMed abstracts, each one listed by PMID above. Published: 2026-10-19. Drafted by language models from published abstracts; not medical advice.